The full product name Cleanance Comedomed Anti-blemish concentrate represents Avène’s most advanced solution for acne-prone skin, whether you’re dealing with sudden breakouts or hormonal pimples. It harnesses 25% of the patented active ingredient Comedoclastin™*, sourced from Milk Thistle seeds, to target imperfections at their root and deliver long-lasting results. Designed for oily skin, this concentrate is suitable for adults and teenagers from 12 years old, and its light, non-greasy texture absorbs quickly to leave the skin matte and comfortable. It can be used alone, in combination, or as a follow-up to acne medications, with high tolerance for sensitive skin and safety for use during pregnancy.
This product is formulated to help reduce the appearance of imperfections and supports a durable action with consistent use, offering effect that can extend up to one year with regular application. The concentration is non-comedogenic, focusing on a targeted treatment approach that respects sensitive skin while delivering noticeable improvements over time.
Key benefits
- Reduces the appearance of imperfections with targeted action at the root of blemishes
- Tightens pores and helps control excess sebum for a smoother complexion
- Non-greasy, fast-absorbing texture leaves skin mattified
- Suitable for adults and teenagers from 12 years old, with high tolerance for sensitive skin
- Can be used alone, in combination, or after acne medications for flexible treatment routines
Ingredients and how they help you
- AVENE THERMAL SPRING WATER (AVÈNE AQUA) — soothing base that supports skin comfort during use
- ISOPROPYL ALCOHOL — helps with quick drying and skin feel after application
- PEG-6, GLYCERIN — humectants that help maintain skin moisture balance
- SILYBUM MARIANUM FRUIT EXTRACT — natural extract associated with anti-blemish properties
- SILICA — adds a soft texture and can help with a refined appearance
- POLYACRYLATE-13, POLYISOBUTENE, POLYSORBATE 20, SORBITAN ISOSTEARATE — formulation aids that help spreadability and texture
- WATER (AQUA) — solvent base for the concentrate
Usage guidance and suitability
Ideal for oily skin types and suitable for adults and teenagers from 12 years old. It is non-comedogenic and can be used alone or in combination with other acne treatments. Safe for use by pregnant women. Always follow the included product instructions for dosage and frequency.
Safety notes: test on a small area before full-face use and discontinue if irritation occurs. If you have a known sensitivity to any ingredient, consult a healthcare professional before use.
* Patent registered. Tolerance and efficacy study under dermatological control on 51 subjects.* Clinical study showing lasting efficacy for 85% of subjects from 1 year with two applications a day on the face, 54 subjects.
How to use Cleanance Comedomed Anti-blemish concentrate
A concise routine to apply the concentrate effectively while minimizing irritation.
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Prepare skin
Begin with a gentle cleanse to remove makeup and impurities before applying the concentrate.
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Apply product
Spread one dose on your fingertips and dab onto the T-zone and cheeks, then use circular motions to boost penetration.
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Even application
Finish by smoothing the product across the cheeks and lower face for even coverage.
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Repeat daily
Reapply morning and evening as part of your skincare routine.
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Safety and precautions
If irritation occurs, discontinue use. Follow the product instructions for dosage and consult a professional if needed.
Frequently Asked Questions
What is Cleanance Comedomed Anti-blemish concentrate best for?
It targets acne-prone skin, reduces the appearance of imperfections, tightens pores, and controls excess sebum with a non-greasy texture.
Who can use this product?
It is designed for adults and teenagers from 12 years old and is safe for pregnant women when used as directed.
How should I apply it?
Apply to a cleansed face twice a day, spreading one dose onto fingertips and dabbing to the T-zone and cheeks, then smoothing across the face. Reapply morning and evening.
Are there any safety precautions?
Test on a small area first. If irritation occurs, discontinue use and consult a healthcare professional. Do not use if known allergies to ingredients exist; keep out of reach of children.
What makes this product different from other acne treatments?
It uses 25% Comedoclastin™ extracted from Milk Thistle seeds to target imperfections at their root and offers long-lasting action with consistent use, up to one year.
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