The Tylenol Extra Strength Cold Relief Day/Night EZTabs offer trusted, around-the-clock relief for cold symptoms with a convenient 40 count formulation. This product is designed for adults 12 years and older who need daytime and nighttime options in one package to help manage common cold symptoms.
Key benefits
- Relieves cold symptoms with daytime and nighttime formulations in EZTabs for easy swallowing
- Includes acetaminophen, dextromethorphan, and phenylephrine in the daytime tablet to address pain, cough suppression, and congestion
- Includes acetaminophen, dextromethorphan, phenylephrine, and chlorpheniramine in the nighttime tablet to address pain, cough suppression, congestion, and allergies
- Total package provides 40 caplets with flexible dosing options for adults
- Clear usage directions on the label to help ensure safe, appropriate use
Ingredients and how they help you
- Acetaminophen — a pain reliever and fever reducer that helps ease general cold discomfort
- Dextromethorphan hydrobromide — a cough suppressant that helps reduce coughing
- Phenylephrine hydrochloride — a decongestant that helps relieve nasal congestion
- Chlorpheniramine maleate — an antihistamine in the nighttime tablet that helps with sneezing and runny nose
- Non-Medicinal Ingredients include cellulose, corn starch, colorants, hypromellose, magnesium stearate, and other excipients that aid tablet formation and stability
Usage guidance and safety
Read the complete label and leaflet before use and follow all directions. Adult use only. Do not use with other products containing any of these ingredients, salicylates, or other cough/cold or pain/fever medications. This product contains acetaminophen, so avoid exceeding a combined total of eight Extra Strength TYLENOL® Cold daytime or nighttime tablets in 24 hours.
Who should consider this product: adults 12 years of age and older who want daytime relief from cold symptoms and a separate nighttime option to help with sleep while managing cold-related discomfort. Quebec regulation information is included on the product page to reflect local guidance for points programs; this statement does not affect the safety or efficacy of the medication.
Storage tips: keep out of reach of children and store at room temperature, away from moisture and heat. If you experience any unusual or severe side effects, discontinue use and consult a health care provider.
Final note: follow the included product instructions for dosing and any timing considerations. This information is provided for informational purposes and should not replace professional medical advice.
This is a medication product intended for temporary relief of cold symptoms; it is not a cure. Always check for potential interactions with other medicines you are taking and consult a health care professional if you have liver disease, heavy alcohol use, or if you are pregnant or nursing.
How to use Extra Strength Cold Relief Day/Night EZTabs
Follow dosing instructions to safely manage cold symptoms with daytime and nighttime tablets.
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Read and prepare
Read the label and leaflet before use; determine whether you will take daytime or nighttime tablets based on the time of day and your symptoms.
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Dose appropriately
Adults 12 years and older should take one to two daytime or nighttime tablets every four hours as needed. Do not exceed eight tablets in 24 hours.
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Avoid interactions
Do not use with other products containing acetaminophen or other cough/cold/pain medications; avoid products with salicylates or substantial alcohol consumption.
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Follow safety notes
If you have liver disease or are pregnant or nursing, consult a health care provider before use. Keep out of reach of children and discontinue if irritation occurs.
Frequently Asked Questions
Who can use this product and how many tablets can I take in 24 hours?
Adult use only, 12 years and older. Take one to two daytime or nighttime tablets every four hours as needed. Do not exceed a combined total of eight Extra Strength TYLENOL Cold daytime or nighttime tablets in 24 hours.
What should I avoid while using this product?
Do not use with other products containing any of these ingredients, salicylates, or other cough/cold or pain/fever medications. Do not exceed the labeled dosage and avoid alcohol use with acetaminophen-containing products.
Are there any safety precautions for this medication?
Adult use only; keep out of reach of children. Read the complete label and leaflet before use. If you have liver disease or drink alcohol regularly, consult a health care provider before use.
What is in the daytime and nighttime tablets and what do they do?
Daytime tablets contain acetaminophen 500 mg, dextromethorphan hydrobromide 10 mg, and phenylephrine hydrochloride 5 mg to relieve pain, suppress cough, and reduce nasal congestion. Nighttime tablets add chlorpheniramine maleate 2 mg for additional relief from runny nose and sneezing.
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