The Buckleys Original Mixture Nighttime 100 mL is a nighttime cough, cold and flu relief product designed to help you sleep through common symptoms. It provides fast-acting relief from dry, hacking coughs, sneezing, runny nose, and nasal and sinus congestion so you can rest easier. This overview translates the product data into clear, useful guidance for adults and those over 12 years old seeking nocturnal symptom relief.
Key benefits
- Fast-acting relief from nighttime coughs and nasal congestion to help you fall asleep.
- Menthol provides a cooling sensation that may ease throat irritation.
- Diphenhydramine hydrochloride offers nocturnal relief from allergy and cold symptoms that disrupt sleep.
- Clear dosing guidelines help you manage intake to avoid exceeding the recommended amount.
- Mixing with equal parts honey is an optional method to improve palatability if preferred.
Ingredients and how they help
- Menthol (22 mg per teaspoonful) — a cooling sensation that can soothe irritated airways and provide temporary relief from coughing.
- Diphenhydramine hydrochloride (12.5 mg per teaspoonful) — an antihistamine that helps reduce sneezing and runny nose at night, aiding sleep.
- Non-Medicinal Ingredients include ammonium carbonate, camphor, glycerin, pine needle oil, and water — these support texture, stability, and flavor while helping deliver the actives.
Usage and suitability
- Shake well before using.
- Take every 6 hours as required, with a typical dose for adults and children over 12 years old being 2 to 3 teaspoons (10 to 100 mL) at or before bedtime.
- Do not exceed 4 doses daily.
- If preferred, mix with equal parts honey for improved palatability.
- Test on a small area if you are sensitive to any active ingredient and consult a health care provider if you have concerns about interactions with other medications.
Product information is provided by the product vendor. This content is a summary for informational purposes only and does not have all possible information about this product. It should not be used as a substitute for advice from health care professionals, as this information alone does not assure that this product is safe, effective, or appropriate for you. For more detailed information on this product, including reported and possible side effects and contraindications, refer to the manufacturer’s monograph, or speak with a health care provider.
Disclaimer: This product is not intended to diagnose, treat, cure, or prevent any disease. Always read and follow the product label. Consult a healthcare professional if you have any health concerns.

















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